The Chargers have won the majority of matchups between the two in the past decade, but the Raiders have won three of the last four.
According to Mike Pickett on the odds-watching Bleacher Report, "If the point spread holds at -1 until kickoff, it will be the first time in eight Monday Nighters that the Oakland Raiders were a favorite."
But Pickett says the line has been moving in favor of San Diego, according to the live football odds display at OddsShark.com, though one book had it as a pick-em late Sunday.
Even if you have no skin in the game, who do you think will win?
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